Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.61 |
| ▸ | FLT3 | P36888 | 13/20 | 0.61 |
| ▸ | KIT | P10721 | 9/20 | 0.61 |
| ▸ | CSF1R | P07333 | 5/20 | 0.61 |
| ▸ | FLT1 | P17948 | 5/20 | 0.61 |
| ▸ | FLT4 | P35916 | 4/20 | 0.61 |
| ▸ | LCK | P06239 | 3/20 | 0.61 |
| ▸ | LYN | P07948 | 3/20 | 0.50 |
| ▸ | BLK | P51451 | 3/20 | 0.50 |
| ▸ | RET | P07949 | 3/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.50 |
| ▸ | MET | P08581 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386467 | 1.00 | KDR (0.61) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668600 | 0.91 | KDR (0.54) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21386487 | 0.91 | KDR (0.54) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21386473 | 0.90 | KDR (0.64) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668695 | 0.90 | KDR (0.64) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL24486691 | 0.90 | KDR (0.53) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21386460 | 0.90 | KDR (0.53) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL24799604 | 0.90 | KDR (0.54) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21386465 | 0.90 | KDR (0.53) | KDRFLT3KITCSF1RFLT1 | |
| SCHEMBL21668599 | 0.89 | KDR (0.53) | KDRFLT3KITCSF1RFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543228-B1 | COMPOUND HAVING ANTICANCER ACTIVITY, AND PREPARATION METHOD AND APPLICATION THEREOF | 3D MEDICINES BEIJING CO LTD (CN) | 2022-12-28 | — | — | EP | disclosed |
| US-11351151-B2 | Compound having anticancer activity and preparation method and application | 3D MEDICINES (BEIJING) CO., LTD. (CN) | 2022-06-07 | — | — | US | disclosed |
| US-20200038371-A1 | COMPOUND HAVING ANTICANCER ACTIVITY AND PREPARATION METHOD AND APPLICATION | 3D MEDICINES (BEIJING) CO., LTD. (CN) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038371-A1 | COMPOUND HAVING ANTICANCER ACTIVITY AND PREPARATION METHOD AND APPLICATION | HDGF, MKI67, LITAF | KDR 421/4885FLT3 49/4885KIT 52/4885 |
| US-11351151-B2 | Compound having anticancer activity and preparation method and application | HDGF, MKI67, LITAF | KDR 440/4885FLT3 49/4885KIT 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.