Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL6839186 | 1.00 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL339425 | 1.00 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21810513 | 0.97 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL6389843 | 0.97 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL11878692 | 0.97 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27842952 | 0.95 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2778330 | 0.95 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1478940 | 0.94 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21642976 | 0.94 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Paraben SCHEMBL2880234 | 0.91 | CA2 (0.73) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034317-A1 | POLYURETHANE ELASTOMER WITH IMPROVED HYDROLYSIS RESISTANCE | COVESTRO DEUTSCHLAND AG (DE) | 2025-01-30 | — | — | US | claimed |
| EP-4444778-A1 | POLYURETHANE ELASTOMER WITH IMPROVED HYDROLYSIS RESISTANCE | Covestro Deutschland AG (DE) | 2024-10-16 | — | — | EP | claimed |
| US-20240117180-A1 | COMPOSTABLE AND ANTIMICROBIAL MATERIAL FOR USE IN PACKAGING MATERIAL | PLASTECHFREE, INC. | 2024-04-11 | — | — | US | claimed |
| CN-117801477-A | Polylactic acid-polyester polyol copolymer compound and preparation method thereof | 万华化学集团股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117683291-A | LFT-G antibacterial PP composite material and preparation method thereof | 长纤（厦门）新材料科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| EP-3748404-B1 | REFLECTIVE STRUCTURE AND APPLICATION THEREOF | NINGBO SOLARTRON TECH CO LTD (CN) | 2023-10-25 | — | — | EP | claimed |
| CN-116554591-A | Biodegradable buffer gas column material master batch and preparation method thereof | 福建省铨丰环保科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116376156-A | Long carbon fiber PPS composite material based on LFT-G technology and preparation method thereof | 长纤（厦门）新材料科技有限公司 | 2023-07-04 | — | — | CN | claimed |
| WO-2023104708-A1 | POLYURETHANE ELASTOMER WITH IMPROVED HYDROLYSIS RESISTANCE | COVESTRO DEUTSCHLAND AG (DE) | 2023-06-15 | — | — | WO | claimed |
| CN-115197403-B | Crystalline degradable polyester based on 1, 3-butanediol and preparation method thereof | 东北师范大学 | 2023-05-26 | — | — | CN | claimed |
| EP-0934007-A4 | — | — | 1999-09-22 | — | — | EP | claimed |
| EP-0934007-A1 | IRRADIATION CONVERSION OF THERMOPLASTIC TO THERMOSET POLYMERS | Zamore, Alan (US) | 1999-08-11 | — | — | EP | claimed |
| US-5750268-A | BLEND OF THERMOPLASTIC RESINS AND HYDROGENATED BLOCK COPOLYMERS | SHELL OIL COMPANY (US) | 1998-05-12 | — | — | US | claimed |
| WO-1998015199-A1 | IRRADIATION CONVERSION OF THERMOPLASTIC TO THERMOSET POLYMERS | ZAMORE ALAN (US) | 1998-04-16 | — | — | WO | claimed |
| EP-0503364-B1 | Method and apparatus for manufacturing tubes reinforced with fibres with a controlled orientation | INST FRANCAIS DU PETROLE (FR) | 1995-06-14 | — | — | EP | claimed |
| US-5307843-A | Extrusion of tubes of fiber-reinforced thermoplastics | INSTITUT FRANCAIS DU PETROLE (FR) | 1994-05-03 | — | — | US | claimed |
| EP-0124452-B1 | PROCESS FOR METALLISING ELECTRICALLY INSULATING PLIABLE FILMS, AND PRODUCTS OBTAINED | RHONE-POULENC CHIMIE (FR) | 1988-03-02 | — | — | EP | claimed |
| EP-0053188-B1 | HEAT RETAINING SHEET | TORAY INDUSTRIES, INC. (JP) | 1985-01-30 | — | — | EP | claimed |
| EP-0055894-A2 | Conductive plastic compositions | Dalton, John Arthur (HK) | 1982-07-14 | — | — | EP | claimed |
| WO-1982001887-A1 | IMPROVEMENTS IN AND RELATING TO COMPOSITIONS | DALTON JOHN A | 1982-06-10 | — | — | WO | claimed |