SCHEMBL2166891

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2168286	0.85	NPC1 (0.66)	NPC1RAB9AALDH1A1HPGDGAA
	SCHEMBL2166723	0.81	ESR2 (1.00)	ESR2NPC1RAB9AALDH1A1HPGD
	SCHEMBL18523587	0.81	ESR2 (0.67)	ESR2NPC1RAB9AALDH1A1HPGD
	SCHEMBL25853393	0.80	ESR2 (0.65)	ESR2NPC1RAB9AALDH1A1HPGD
	SCHEMBL23316808	0.78	ESR2 (0.76)	ESR2NPC1RAB9AALDH1A1HPGD
	SCHEMBL15068480	0.78	MIF (0.46)	ESR2NPC1RAB9AALDH1A1HPGD
	SCHEMBL15066651	0.78	AKR1B10 (0.41)	ESR2NPC1L3MBTL1MIFPOLB
	SCHEMBL11297212	0.77	ADORA3 (0.51)	ESR2NPC1RAB9AALDH1A1HPGD
	SCHEMBL16520509	0.76	MIF (0.83)	ESR2NPC1RAB9AALDH1A1HPGD
	SCHEMBL802632	0.75	ESR2 (0.56)	ESR2NPC1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.