SCHEMBL21668951

SCHEMBL21668951

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc4c(c3)oc3ccc(-n5c6ccccc6c6ccc7c8ccccc8n(-c8ccccc8)c7c65)cc34)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
KMT2A Q03164 6/20 0.34
ALDH1A1 P00352 5/20 0.34
MAPT P10636 5/20 0.34
MEN1 O00255 4/20 0.34
HPGD P15428 4/20 0.34
NTSR1 P30989 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
MAPK1 P28482 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 3/20 0.33
CHEK2 O96017 1/20 0.31
PTGER4 P35408 1/20 0.31
GLA P06280 1/20 0.31
AHR P35869 1/20 0.31
MMP12 P39900 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25627917 0.98 KMT2A (0.35) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL25628150 0.96 KDM4E (0.35) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL25627972 0.96 KDM4E (0.37) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL21883364 0.95 KDM4E (0.38) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL21668782 0.94 KDM4E (0.37) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL25628096 0.93 KMT2A (0.37) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL25966055 0.93 MAPT (0.37) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL26146815 0.92 KDM4E (0.34) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL24078246 0.92 MEN1 (0.36) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL25966053 0.92 MEN1 (0.38) KDM4EL3MBTL1ATMKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element LT MATERIALS CO., LTD. (KR) 2022-07-12 US disclosed
EP-3611173-B1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT LT MATERIALS CO LTD (KR) 2021-07-28 EP disclosed
US-20210057651-A1 ORGANIC LIGHT EMITTING DEVICE, METHOD FOR MANUFACTURING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2021-02-25 US disclosed
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2020-12-03 US disclosed
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT HEESUNG MATERIAL LTD. (KR) 2020-04-16 US disclosed
EP-3611173-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT Heesung Material Ltd. (KR) 2020-02-19 EP disclosed
EP-3604297-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME Heesung Material Ltd. (KR) 2020-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element CRY1, CYBA, L1CAM KDM4E 3489/4885L3MBTL1 838/4885ATM 2594/4885
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT CRY1, CYBA, L1CAM KDM4E 3489/4885L3MBTL1 838/4885ATM 2594/4885
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 KDM4E 2341/4885L3MBTL1 1142/4885ATM 2995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.