SCHEMBL21669441

SCHEMBL21669441

O=C1c2ccc3c4c(ccc(c24)C(=O)N1C(c1ccccc1)c1ccccc1)C(O)N(C(CO)CO)C3=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNA5 P22460 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21226291 0.82 MEN1 (0.38) MEN1KMT2A
SCHEMBL21449270 0.80 KDM4E (0.33)
SCHEMBL21449399 0.79 ALDH1A1 (0.36) MEN1KMT2A
SCHEMBL19749841 0.78 ALDH1A1 (0.32) MEN1KMT2A
SCHEMBL21669398 0.75 ANPEP (0.49)
SCHEMBL21449276 0.75 KDM4E (0.32)
SCHEMBL22014087 0.73 HPGD (0.46) MEN1KMT2AKCNA5
SCHEMBL21669393 0.73 MAPT (0.39) MEN1KMT2A
SCHEMBL23312264 0.70 KDM4E (0.35) MEN1KMT2A
SCHEMBL22893523 0.69 MDM2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11061341-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-07-13 US disclosed
US-20200041918-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-02-06 US disclosed