Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21019432 | 0.88 | MEN1 (0.43) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL4471060 | 0.79 | MEN1 (0.51) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL21583755 | 0.74 | KMT2A (0.47) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL20195031 | 0.74 | HPGD (0.39) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL21669441 | 0.73 | MEN1 (0.32) | MEN1KMT2AKCNA5 | |
| SCHEMBL21583744 | 0.72 | RAB9A (0.45) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL20427974 | 0.72 | KCNA5 (0.43) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL18576659 | 0.72 | MME (0.44) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL19790309 | 0.71 | MEN1 (0.39) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL20924684 | 0.71 | L3MBTL1 (0.62) | HPGDLMNARAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020100959-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE | 日本新薬株式会社 | 2020-05-22 | — | — | WO | disclosed |