Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670282 | 1.00 | RAB9A (0.54) | RAB9APOLBGAAALDH1A1LMNA | |
| SCHEMBL21670298 | 0.92 | RAB9A (0.53) | RAB9APOLBGAAALDH1A1LMNA | |
| SCHEMBL21669801 | 0.92 | RAB9A (0.53) | RAB9APOLBGAAALDH1A1LMNA | |
| SCHEMBL21669803 | 0.89 | KMT2A (0.54) | RAB9APOLBGAAALDH1A1LMNA | |
| SCHEMBL21670296 | 0.89 | KMT2A (0.54) | RAB9APOLBGAAALDH1A1LMNA | |
| SCHEMBL21670284 | 0.86 | RAB9A (0.53) | RAB9APOLBGAALMNA | |
| SCHEMBL21670439 | 0.86 | RAB9A (0.53) | RAB9APOLBGAALMNA | |
| SCHEMBL21670352 | 0.86 | RAB9A (0.52) | RAB9AGAAALDH1A1LMNAMGLL | |
| SCHEMBL21669774 | 0.86 | RAB9A (0.52) | RAB9AGAAALDH1A1LMNAMGLL | |
| SCHEMBL21669772 | 0.84 | RAB9A (0.53) | RAB9APOLBALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |