Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RHOA | P61586 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21669774 | 1.00 | RAB9A (0.52) | RAB9AALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL21670290 | 0.93 | RAB9A (0.48) | RAB9AALDH1A1SMN1; SMN2TSHRRHOA | |
| SCHEMBL21669944 | 0.93 | RAB9A (0.48) | RAB9AALDH1A1SMN1; SMN2TSHRRHOA | |
| SCHEMBL21670350 | 0.91 | RAB9A (0.53) | RAB9AALDH1A1SMN1; SMN2TSHRRHOA | |
| SCHEMBL21669772 | 0.91 | RAB9A (0.53) | RAB9AALDH1A1SMN1; SMN2TSHRRHOA | |
| SCHEMBL21670300 | 0.90 | ALDH1A1 (0.47) | RAB9AALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL21669960 | 0.90 | ALDH1A1 (0.47) | RAB9AALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL21670403 | 0.87 | RAB9A (0.54) | RAB9AALDH1A1SMN1; SMN2TSHRRHOA | |
| SCHEMBL21670294 | 0.86 | EPHX2 (0.64) | RAB9AALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL21669802 | 0.86 | RAB9A (0.54) | RAB9AALDH1A1LMNAGAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |