Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670254 | 1.00 | LMNA (0.70) | LMNASMN1; SMN2CYP2C19USP2GAA | |
| SCHEMBL610121 | 0.88 | MAPT (0.77) | LMNASMN1; SMN2CYP2C19ALDH1A1AKR1C3 | |
| SCHEMBL21669903 | 0.88 | MAPT (0.77) | LMNASMN1; SMN2CYP2C19ALDH1A1AKR1C3 | |
| SCHEMBL4701073 | 0.88 | MAPT (0.77) | LMNASMN1; SMN2CYP2C19ALDH1A1AKR1C3 | |
| SCHEMBL21670262 | 0.86 | LMNA (0.70) | LMNASMN1; SMN2CYP2C19ALDH1A1AKR1C3 | |
| SCHEMBL611585 | 0.82 | TDP1 (0.69) | LMNASMN1; SMN2CYP2C19USP2GAA | |
| SCHEMBL611586 | 0.82 | TDP1 (0.69) | LMNASMN1; SMN2CYP2C19USP2GAA | |
| SCHEMBL4806165 | 0.82 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19ALDH1A1HTT | |
| SCHEMBL612760 | 0.82 | CYP2C19 (1.00) | SMN1; SMN2CYP2C19GAAALDH1A1HSD17B10 | |
| SCHEMBL611344 | 0.81 | KMT2A (0.78) | LMNASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |