SCHEMBL21670532

SCHEMBL21670532

CCOc1ccc(-c2cc(-c3ccc(Nc4ccccc4)cc3)cc(-c3ccc(Br)cc3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 2/20 0.51
MCL1 Q07820 5/20 0.50
SLC2A1 P11166 2/20 0.49
KDM4E B2RXH2 4/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
POLB P06746 1/20 0.48
OPRM1 P35372 1/20 0.48
OPRD1 P41143 1/20 0.48
RAD52 P43351 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
RAB9A P51151 3/20 0.46
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46
TUBB3 Q13509 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30526009 0.88 ACP1 (0.51) ACP1SLC2A1KDM4EMAPTKMT2A
SCHEMBL21670592 0.88 ACP1 (0.51) ACP1SLC2A1KDM4EMAPTKMT2A
SCHEMBL21670513 0.88 ACP1 (0.51) ACP1SLC2A1KDM4EMAPTKMT2A
SCHEMBL28349547 0.84 MCL1 (0.46) ACP1MCL1KMT2ARAB9ANPC1
SCHEMBL11781553 0.83 NPC1 (0.57) MCL1KDM4EMAPTRAB9ANPC1
SCHEMBL28352770 0.82 RAB9A (0.47) ACP1SLC2A1KDM4EMAPTKMT2A
SCHEMBL30525979 0.80 KDM4E (0.52) MCL1SLC2A1KDM4EMAPTKMT2A
SCHEMBL21670540 0.80 KDM4E (0.52) MCL1SLC2A1KDM4EMAPTKMT2A
SCHEMBL21670587 0.77 MCL1 (0.43) MCL1KDM4EMAPTKMT2ARAB9A
SCHEMBL9479637 0.77 MAPT (0.63) SLC2A1KDM4EMAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed