SCHEMBL21670587

SCHEMBL21670587

CCOc1ccc(-c2cc(-c3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc(-c3ccc(Br)cc3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.43
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 3/20 0.43
GAA P10253 3/20 0.43
MAPT P10636 5/20 0.42
TP53 P04637 3/20 0.42
PTGS2 P35354 1/20 0.40
THRB P10828 1/20 0.40
ADORA3 P0DMS8 1/20 0.39
NPC1 O15118 2/20 0.39
LMNA P02545 3/20 0.39
HPGD P15428 2/20 0.39
MGAM O43451 2/20 0.39
SI P14410 2/20 0.39
MGAM2 Q2M2H8 2/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21670559 0.88 KDM4E (0.43) MCL1KDM4EALDH1A1GAAMAPT
SCHEMBL21670565 0.88 NPSR1 (0.43) KDM4EALDH1A1GAAMAPTTP53
SCHEMBL29048657 0.83 MGAM (0.49) MCL1KDM4EALDH1A1GAAMAPT
SCHEMBL15703027 0.82 NQO1 (0.52) KDM4EALDH1A1GAAMAPTTP53
SCHEMBL12680650 0.81 NQO1 (0.54) KDM4EALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL19607554 0.81 NQO1 (0.54) KDM4EALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL29575861 0.79 MCL1 (0.54) MCL1KDM4EALDH1A1GAAMAPT
SCHEMBL21670547 0.79 LMNA (0.45) MCL1KDM4EALDH1A1GAAMAPT
SCHEMBL21670568 0.79 LMNA (0.45) MCL1KDM4EALDH1A1GAAMAPT
SCHEMBL30526020 0.79 LMNA (0.45) MCL1KDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed