Diphenylamine

Diphenylamine

SCHEMBL8196609

COc1ccc(-c2cc(-c3ccccc3)cc(-c3ccc(OC)cc3OC)n2)c(OC)c1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.56
MEN1 O00255 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 4/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
ATM Q13315 1/20 0.56
KDM4E B2RXH2 6/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
ALDH1A1 P00352 2/20 0.51
TP53 P04637 2/20 0.51
HTT P42858 2/20 0.51
HSD17B10 Q99714 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
CYP1A1 P04798 4/20 0.50
CYP1B1 Q16678 4/20 0.50
CYP1A2 P05177 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21670541 0.96 MEN1 (0.52) KMT2AMEN1SMN1; SMN2MAPTNPC1
SCHEMBL30525969 0.96 MEN1 (0.52) KMT2AMEN1SMN1; SMN2MAPTNPC1
SCHEMBL30525956 0.87 KMT2A (0.44) KMT2AMEN1SMN1; SMN2MAPTNPC1
SCHEMBL21670526 0.87 KMT2A (0.44) KMT2AMEN1SMN1; SMN2MAPTNPC1
SCHEMBL21670550 0.83 FGFR2 (0.45) KMT2AMEN1SMN1; SMN2MAPTNPC1
SCHEMBL30525978 0.83 FGFR2 (0.45) KMT2AMEN1SMN1; SMN2MAPTNPC1
SCHEMBL29048655 0.83 FGFR2 (0.50) KMT2AMEN1SMN1; SMN2MAPTNPC1
SCHEMBL21670529 0.82 CYP1A2 (0.49) ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL21670542 0.82 STK10 (0.49) KMT2AMEN1SMN1; SMN2MAPTATM
SCHEMBL30525998 0.82 STK10 (0.49) KMT2AMEN1SMN1; SMN2MAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6015907-A PHOTOSTABLE IMAGING DYES FOR ACID-MEDIATED MEDIA, ALSO FOR PHOTOSENSITIZING ONIUM SALTS TO VISIBLE BLUE RADIATION POLAROID CORPORATION (US) 2000-01-18 US disclosed