SCHEMBL29048655

SCHEMBL29048655

COc1ccc(-c2cc(-c3ccc(Nc4ccccc4)cc3)ccn2)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR2 P21802 2/20 0.50
MEN1 O00255 4/20 0.49
NPC1 O15118 4/20 0.49
RAB9A P51151 4/20 0.49
KMT2A Q03164 4/20 0.49
MAPT P10636 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NFKB1 P19838 2/20 0.49
NFKB2 Q00653 2/20 0.49
RELA Q04206 2/20 0.49
ATM Q13315 1/20 0.49
CSNK2A1 P68400 1/20 0.47
TGFBR1 P36897 1/20 0.44
SYK P43405 2/20 0.44
CYP1A1 P04798 3/20 0.43
CYP1B1 Q16678 3/20 0.43
PIK3CA P42336 1/20 0.43
PIK3CB P42338 1/20 0.43
PIK3CG P48736 1/20 0.43
ALDH1A1 P00352 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048643 0.87 FGFR2 (0.50) FGFR2MEN1NPC1RAB9AKMT2A
SCHEMBL30525969 0.86 MEN1 (0.52) FGFR2MEN1NPC1RAB9AKMT2A
SCHEMBL21670541 0.86 MEN1 (0.52) FGFR2MEN1NPC1RAB9AKMT2A
SCHEMBL29048642 0.86 FGFR2 (0.50) FGFR2MEN1KMT2AATMTGFBR1
SCHEMBL29048609 0.84 KDM4E (0.45) FGFR2MEN1NPC1RAB9AKMT2A
Diphenylamine SCHEMBL8196609 0.83 KMT2A (0.56) MEN1NPC1RAB9AKMT2AMAPT
SCHEMBL29048640 0.82 GCGR (0.41) FGFR2NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL29048626 0.82 CYP2D6 (0.44) FGFR2CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL29048632 0.81 MAPT (0.43) FGFR2NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL17144531 0.80 CYP1A1 (0.60) MEN1NPC1RAB9AKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed