SCHEMBL21670565

SCHEMBL21670565

CCOc1ccc(-c2cc(-c3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc(-c3ccc(Cl)cc3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 5/20 0.42
TP53 P04637 3/20 0.42
CHRNA7 P36544 2/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
PTGS2 P35354 1/20 0.40
CACNA2D1 P54289 1/20 0.40
ATM Q13315 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN10A Q9Y5Y9 1/20 0.39
CXCR1 P25024 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14805210 0.88 CHRNA7 (0.50) KDM4EALDH1A1GAAMAPTTP53
SCHEMBL21670587 0.88 MCL1 (0.43) KDM4EALDH1A1GAAMAPTTP53
SCHEMBL21670559 0.88 KDM4E (0.43) NPSR1KDM4EALDH1A1GAAMAPT
SCHEMBL29048614 0.83 MGAM (0.49) KDM4EALDH1A1GAAMAPTKMT2A
SCHEMBL12680650 0.81 NQO1 (0.54) NPSR1KDM4EALDH1A1MAPTKMT2A
SCHEMBL19607554 0.81 NQO1 (0.54) NPSR1KDM4EALDH1A1MAPTKMT2A
SCHEMBL21670506 0.81 AGPAT2 (0.43) NPSR1KDM4EGAAMAPTADORA3
SCHEMBL21670547 0.79 LMNA (0.45) NPSR1KDM4EALDH1A1GAAMAPT
SCHEMBL21670568 0.79 LMNA (0.45) NPSR1KDM4EALDH1A1GAAMAPT
SCHEMBL30526041 0.79 LMNA (0.45) NPSR1KDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed