SCHEMBL21670593

SCHEMBL21670593

CCOc1cc(OCC)c(-c2cc(-c3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc(-c3cc(Cl)c(OCC)cc3OCC)n2)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
MAPT P10636 4/20 0.37
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AGPAT2 O15120 3/20 0.36
GRM5 P41594 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
ALOX12 P18054 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
TUBB4A P04350 2/20 0.34
TUBB P07437 2/20 0.34
TUBA3C P0DPH7 2/20 0.34
TUBA1B P68363 2/20 0.34
TUBA4A P68366 2/20 0.34
TUBB4B P68371 2/20 0.34
TUBB3 Q13509 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525996 1.00 ENPP3 (0.40) ENPP3ENPP1MAPTRAB9AATM
SCHEMBL29048656 0.90 ENPP3 (0.43) ENPP3ENPP1MAPTRAB9AATM
SCHEMBL21670557 0.90 ENPP3 (0.43) ENPP3ENPP1MAPTRAB9AATM
SCHEMBL30525985 0.90 ENPP3 (0.43) ENPP3ENPP1MAPTRAB9AATM
SCHEMBL21670506 0.86 AGPAT2 (0.43) ENPP3ENPP1MAPTAGPAT2GRM5
SCHEMBL21670547 0.82 LMNA (0.45) ENPP3ENPP1MAPTRAB9AGRM5
SCHEMBL30526020 0.82 LMNA (0.45) ENPP3ENPP1MAPTRAB9AGRM5
SCHEMBL21670568 0.82 LMNA (0.45) ENPP3ENPP1MAPTRAB9AGRM5
SCHEMBL30526041 0.82 LMNA (0.45) ENPP3ENPP1MAPTRAB9AGRM5
SCHEMBL21670563 0.81 ENPP1 (0.56) ENPP3ENPP1MAPTGRM5NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed