Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670752 | 0.90 | DRD2 (0.43) | DRD2KDM2BEPHX2TAAR1DRD3 | |
| SCHEMBL22733591 | 0.80 | HTR2A (0.46) | DRD2HPGDSIDH1GRM2 | |
| SCHEMBL20522556 | 0.79 | GRM2 (0.42) | DRD2HPGDSIDH1KDM2BGRM2 | |
| SCHEMBL4609520 | 0.76 | PTGDR2 (0.50) | DRD2 | |
| SCHEMBL20522558 | 0.75 | ALDH1A1 (0.53) | IDH1 | |
| SCHEMBL4608591 | 0.74 | PTGDR2 (0.52) | — | |
| SCHEMBL21670589 | 0.74 | GRM2 (0.47) | DRD2TAAR1KCNH2GRM2 | |
| SCHEMBL22733431 | 0.71 | HTR2A (0.45) | DRD2EPHX2GRM2 | |
| SCHEMBL6437932 | 0.71 | ESR2 (0.45) | — | |
| SCHEMBL25705289 | 0.70 | MEN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604267-A1 | AROMATIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-02-05 | — | — | EP | disclosed |