SCHEMBL21671435

SCHEMBL21671435

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5oc6cc(-n7c8ccccc8c8ccccc87)ccc6c45)cc3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.35
KDM4E B2RXH2 4/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
ATM Q13315 2/20 0.35
BACE1 P56817 1/20 0.35
MAPT P10636 5/20 0.33
MAPK1 P28482 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
TSHR P16473 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK14 Q16539 1/20 0.32
DUSP3 P51452 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25954866 0.98 PTGER4 (0.34) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL25954874 0.97 BACE1 (0.33) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL25954311 0.97 PTGER4 (0.33) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL25954868 0.97 BACE1 (0.33) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL25954312 0.96 BACE1 (0.33) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL21671172 0.96 BACE1 (0.33) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL25954389 0.96 BACE1 (0.33) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL21666806 0.96 PTGER4 (0.34) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL25720239 0.96 PTGER4 (0.36) PTGER4KDM4EL3MBTL1ATMBACE1
SCHEMBL25926550 0.96 PTGER4 (0.36) PTGER4KDM4EL3MBTL1ATMBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11527723-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-12-13 US disclosed
WO-2022239930-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE 엘티소재주식회사 2022-11-17 WO disclosed
EP-3604296-B1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT LT MATERIALS CO LTD (KR) 2021-07-28 EP disclosed
US-20210057651-A1 ORGANIC LIGHT EMITTING DEVICE, METHOD FOR MANUFACTURING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2021-02-25 US disclosed
US-20200123133-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME HEESUNG MATERIAL LTD. (KR) 2020-04-23 US disclosed
EP-3604298-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME Heesung Material Ltd. (KR) 2020-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200123133-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 PTGER4 717/4885KDM4E 2341/4885L3MBTL1 1142/4885
US-11527723-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 PTGER4 717/4885KDM4E 2341/4885L3MBTL1 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.