SCHEMBL21673071

SCHEMBL21673071

CN1CCC[C@@H](C(=O)O)[C@H]1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 1/20 0.36
ACE P12821 3/20 0.35
PEPD P12955 1/20 0.34
L3MBTL3 Q96JM7 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA5 P30532 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17756092 0.79 HSD17B10 (0.38) MEN1KMT2AALDH1A1
SCHEMBL23081228 0.79 ALDH1A1 (0.36) MEN1BLMKMT2AALDH1A1ACE
SCHEMBL16759353 0.79 ALDH1A1 (0.36) MEN1BLMKMT2AALDH1A1ACE
SCHEMBL28554073 0.76 ACE (0.40) ACE
SCHEMBL9821422 0.75 PEPD (0.38) MEN1BLMKMT2AALDH1A1ACE
SCHEMBL16207902 0.75 SMN1; SMN2 (0.36) ALDH1A1ACEPEPDCHRNB2CHRNA5
SCHEMBL21676666 0.75 CHRNB2 (0.38) PEPDCHRNB2CHRNA5CHRNA7CHRNA4
SCHEMBL7519810 0.73 SLC1A2 (0.36) MEN1BLMKMT2AALDH1A1
SCHEMBL4895931 0.71 TDP1 (0.36) ALDH1A1
SCHEMBL17795772 0.71 TDP1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3831823-A1 PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) 2021-06-09 EP disclosed
EP-3831824-A1 PREPARATION AND APPLICATION OF CLASS OF N-CONTAINING HETEROCYCLIC COMPOUNDS HAVING IMMUNOREGULATORY FUNCTION Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) 2021-06-09 EP disclosed
WO-2020025030-A1 PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION 上海轶诺药业有限公司 2020-02-06 WO disclosed
WO-2020024997-A1 PREPARATION AND APPLICATION OF CLASS OF N-CONTAINING HETEROCYCLIC COMPOUNDS HAVING IMMUNOREGULATORY FUNCTION 上海轶诺药业有限公司 2020-02-06 WO disclosed