⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629218 | 1.00 | — | — | |
| SCHEMBL2167346 | 1.00 | — | — | |
| SCHEMBL3003413 | 0.84 | F2 (0.56) | — | |
| SCHEMBL3003418 | 0.84 | F2 (0.56) | — | |
| SCHEMBL2789580 | 0.84 | ALDH1A1 (0.62) | — | |
| SCHEMBL641747 | 0.84 | ALDH1A1 (0.62) | — | |
| SCHEMBL11153607 | 0.82 | F2 (0.55) | — | |
| SCHEMBL11153560 | 0.82 | F2 (0.55) | — | |
| SCHEMBL21959834 | 0.82 | HCAR2 (0.39) | — | |
| SCHEMBL10745928 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440237-A | Self-repairing polymer, preparation method and application thereof, self-repairing coating, cable and communication equipment | 武汉烽火锐拓科技有限公司 | 2024-08-06 | — | — | CN | claimed |
| US-20160175274-A1 | TREATING AN ATYPICAL PROTEIN KINASE C ENZYME ABNORMALITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-06-23 | — | — | US | claimed |
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-10 | — | — | US | claimed |
| US-6723743-B1 | TREATING PATIENT SUFFERING FROM RHEUMATOID ARTHRITIS, PSORIASIS, BRONCHIAL ASTHMA, ALZHEIMER'S DISEASE, MYOCARDIAL INFARCTION OR ATHEROSCLEROSIS | NEUROGEN CORPORATION | 2004-04-20 | — | — | US | claimed |
| CN-118440237-A | Self-repairing polymer, preparation method and application thereof, self-repairing coating, cable and communication equipment | 武汉烽火锐拓科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-10688063-B2 | Treating and/or preventing insulin-resistance related weight gain | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-06-23 | — | — | US | disclosed |
| CN-107311985-B | N- [ (3-heterocyclyl) acryloyl ] phenyl nicotinamide derivative and application thereof | 西华大学 | 2019-11-12 | — | — | CN | disclosed |
| CN-107118185-B | N- [ (3-heterocyclic group) acryloyl ] phenyl acrylamide derivative and application thereof | 西华大学 | 2019-05-03 | — | — | CN | disclosed |
| US-20180028488-A1 | TREATING AND/OR PREVENTING INSULIN-RESISTANCE RELATED WEIGHT GAIN | UNIVERSITY OF SOUTH FLORIDA (US) | 2018-02-01 | — | — | US | disclosed |
| CN-107311985-A | N [(3 heterocyclic radical) acryloyl group] phenyl nicotinamide derivatives and its application | 西华大学 | 2017-11-03 | — | — | CN | disclosed |
| US-9795584-B2 | Treating an atypical protein kinase C enzyme abnormality | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-10-24 | — | — | US | disclosed |
| CN-107118185-A | N [(3 heterocyclic radical) acryloyl group] phenylacryloyl amine derivants and its application | 西华大学 | 2017-09-01 | — | — | CN | disclosed |
| EP-0561413-A1 | Erythromycin deriatives, preparation and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5175150-A | Stimulating digective contraction | KITASATO, KENKYUSHO (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5008249-A | Administering anhydroerythromycin derivative | KITASATO KENKYUSHO (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4948782-A | A method of promoting the growth of domestic animals with erythromycin derivative containing composition | KITASATO KENKYUSHO (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0186915-B1 | NOVEL ALLYLIC AMINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-08-08 | — | — | EP | disclosed |
| EP-0215355-A2 | Erythromycin derivative and process for preparing the same | KITASATO KENKYUSHO (JP) | 1987-03-25 | — | — | EP | disclosed |
| EP-0213617-A2 | Digestive tract contractile motion stimulant | KITASATO KENKYUSHO (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0186915-A2 | Novel allylic amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-07-09 | — | — | EP | disclosed |