Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23066443 | 0.68 | NSD2 (0.50) | AKR1C3GRM5MAOBNSD2NPC1 | |
| SCHEMBL21674069 | 0.68 | MEN1 (0.47) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21639644 | 0.66 | CA12 (0.48) | NPC1RAB9A | |
| SCHEMBL21639579 | 0.65 | APEX1 (0.52) | AKR1C3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21639501 | 0.65 | RAB9A (0.51) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21639550 | 0.65 | MAOA (0.52) | AKR1C3MAOBNPC1MAOARAB9A | |
| SCHEMBL6168742 | 0.64 | NPC1 (0.66) | EGFRPIK3CAMAOBNPC1ADORA3 | |
| SCHEMBL30395353 | 0.64 | NPC1 (0.66) | EGFRPIK3CAMAOBNPC1ADORA3 | |
| SCHEMBL21639509 | 0.63 | TSHR (0.52) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL23078823 | 0.63 | MRGPRX4 (0.42) | AKR1C3NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604281-A1 | 2(1H)-QUINOLINONE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |