Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.63 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308629 | 0.97 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL25895424 | 0.95 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL25896290 | 0.95 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL25896084 | 0.95 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL25304177 | 0.95 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL23079680 | 0.92 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL25895430 | 0.91 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL21674268 | 0.90 | NPC1 (0.77) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL23079988 | 0.90 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL23079708 | 0.90 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129059-A1 | PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2025-04-24 | — | — | US | disclosed |
| EP-4464702-A1 | PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023136295-A1 | PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | 保土谷化学工業株式会社 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023136295-A1 | PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | 保土谷化学工業株式会社 | 2023-07-20 | — | — | WO | disclosed |
| WO-2020027389-A1 | ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | (주)피엔에이치테크 | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129059-A1 | PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | LEF1, YBX1, YBX3 | NPC1 3855/4885RAB9A 3697/4885MEN1 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.