Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25896084 | 1.00 | NPC1 (0.58) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL25895424 | 1.00 | NPC1 (0.58) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL25304177 | 1.00 | NPC1 (0.58) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL18308629 | 0.98 | NPC1 (0.59) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL25895430 | 0.96 | NPC1 (0.54) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL21674266 | 0.95 | NPC1 (0.63) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL25895426 | 0.92 | NPC1 (0.50) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL23079988 | 0.91 | NPC1 (0.59) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL23079708 | 0.91 | NPC1 (0.59) | NPC1MEN1KMT2ARAB9AATM | |
| SCHEMBL14225278 | 0.91 | ALDH1A1 (0.51) | NPC1MEN1KMT2ARAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136295-A1 | PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | 保土谷化学工業株式会社 | 2023-07-20 | — | — | WO | disclosed |