SCHEMBL2167461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2151276	0.90	TDP1 (0.53)	CA1CA2ALDH1A1MAPTHDAC11
	SCHEMBL2197030	0.86	CA1 (0.59)	CA1CA2ALDH1A1HPGDLMNA
	SCHEMBL2150830	0.84	CA1 (0.40)	CA1CA2ALDH1A1MAPTHDAC8
	SCHEMBL2151087	0.83	HDAC11 (0.49)	CA1CA2ALDH1A1MAPTHDAC11
	SCHEMBL3134433	0.83	CA1 (0.41)	CA1CA2ALDH1A1MAPTHDAC8
	SCHEMBL3134357	0.83	CA1 (0.41)	CA1CA2ALDH1A1MAPTHDAC8
	SCHEMBL3125056	0.83	MEN1 (0.44)	CA1CA2ALDH1A1MAPTSMN1; SMN2
	SCHEMBL3133160	0.83	CA1 (0.46)	CA1CA2HPGDLMNARAB9A
	SCHEMBL15945985	0.82	HDAC11 (0.51)	CA1CA2ALDH1A1MAPTHDAC11
	SCHEMBL17737797	0.81	THRB (0.54)	CA1CA2MAPTGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.