Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167567 | 0.95 | SMN1; SMN2 (0.36) | ADRA1ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2180684 | 0.94 | ADRA1A (0.37) | ADRA1ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2168910 | 0.92 | SMN1; SMN2 (0.42) | ADRA1ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18887342 | 0.89 | ADRA1A (0.36) | ADRA1ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2169080 | 0.87 | MCHR1 (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2168083 | 0.87 | KDM5A (0.33) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2169234 | 0.86 | MEN1 (0.34) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2169831 | 0.86 | HPGD (0.40) | ADRA1ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2171193 | 0.86 | HPGD (0.39) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2168080 | 0.85 | POLB (0.36) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |