Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169234 | 0.94 | MEN1 (0.34) | KDM4EPOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL2168080 | 0.90 | POLB (0.36) | KDM4EPOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL2169831 | 0.89 | HPGD (0.40) | KDM4EPOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL2171193 | 0.89 | HPGD (0.39) | KDM4EPOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL2180684 | 0.89 | ADRA1A (0.37) | HRH3NPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL18887351 | 0.88 | MCHR1 (0.36) | MCHR1HRH3NPC1ALDH1A1HPGD | |
| SCHEMBL2168910 | 0.88 | SMN1; SMN2 (0.42) | KDM4EPOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL2169211 | 0.88 | ITK (0.38) | KDM4EPOLBMAPTALDH1A1HPGD | |
| SCHEMBL2167682 | 0.87 | HPGD (0.38) | KDM4EPOLBMAPTNPC1ALDH1A1 | |
| SCHEMBL2168083 | 0.87 | KDM5A (0.33) | KDM4EPOLBMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |