Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882091 | 1.00 | POLB (0.53) | POLBLMNAMAPTNPSR1USP2 | |
| SCHEMBL805315 | 0.86 | MEN1 (0.52) | POLBLMNAMAPTNPSR1CYP1A2 | |
| SCHEMBL14130193 | 0.84 | HTT (0.56) | POLBLMNAMAPTNPSR1USP2 | |
| SCHEMBL20328401 | 0.83 | KDM4E (0.57) | LMNAMAPTMEN1KMT2APLA2G4B | |
| SCHEMBL14189198 | 0.83 | USP2 (0.68) | POLBLMNAMAPTNPSR1USP2 | |
| SCHEMBL18309828 | 0.83 | CYP1A2 (0.72) | POLBLMNAMAPTNPSR1USP2 | |
| SCHEMBL11664192 | 0.81 | KMT2A (0.62) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL19443225 | 0.80 | L3MBTL1 (0.50) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL2032040 | 0.79 | POLB (0.54) | POLBLMNAMAPTNPSR1USP2 | |
| SCHEMBL26704551 | 0.79 | POLB (0.50) | POLBLMNAMAPTNPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2711381-B1 | NOVEL COMPOUND, COMPOSITION CONTAINING SAID COMPOUND, AND CURED PRODUCT | MITSUI CHEMICALS INC (JP) | 2020-02-05 | — | — | EP | disclosed |