SCHEMBL21676138

SCHEMBL21676138

c1ccc2cc(-n3c4ccccc4c4c3ccc3c5c6ccccc6ccc5n(-c5ccc6c(c5)-c5cccc7cccc-6c57)c34)ccc2c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
TSHR P16473 3/20 0.36
MAPK1 P28482 3/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 3/20 0.36
CASP1 P29466 2/20 0.36
HIF1A Q16665 2/20 0.36
TP53 P04637 1/20 0.36
CASP7 P55210 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.33
ANPEP P15144 1/20 0.32
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
BRD1 O95696 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21676137 1.00 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676064 0.94 ANPEP (0.34) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676132 0.94 ANPEP (0.34) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676143 0.94 L3MBTL1 (0.36) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676096 0.94 L3MBTL1 (0.36) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676134 0.92 ALDH1A1 (0.34) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676152 0.91 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676167 0.91 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL21676123 0.91 PDE6D (0.35) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL17341218 0.90 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020026133-A1 POLYCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-06 WO disclosed