Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21144716 | 0.89 | ALDH1A1 (0.46) | ACACBKDM4EALDH1A1CD274CTSC | |
| SCHEMBL21144718 | 0.89 | ALDH1A1 (0.46) | ACACBKDM4EALDH1A1CD274CTSC | |
| SCHEMBL18930237 | 0.85 | KDM4E (0.43) | ACACBKDM4EALDH1A1CD274CTSC | |
| SCHEMBL13267195 | 0.84 | ALDH1A1 (0.50) | ACACBALDH1A1 | |
| SCHEMBL21144737 | 0.78 | CD274 (0.49) | ACACBKDM4EALDH1A1CD274CTSC | |
| SCHEMBL21144738 | 0.78 | CD274 (0.49) | ACACBKDM4EALDH1A1CD274CTSC | |
| SCHEMBL21144956 | 0.78 | FPR1 (0.45) | ACACBCTSCKCNH2CYP2D6DPP4 | |
| SCHEMBL21144957 | 0.78 | FPR1 (0.45) | ACACBCTSCKCNH2CYP2D6DPP4 | |
| SCHEMBL21144878 | 0.78 | SLC1A2 (0.45) | ACACBALDH1A1KCNH2 | |
| SCHEMBL21144875 | 0.78 | SLC1A2 (0.45) | ACACBALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |