Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169831 | 0.98 | HPGD (0.40) | HPGDALOX15SMN1; SMN2KDM4EPOLB | |
| SCHEMBL2171193 | 0.95 | HPGD (0.39) | HPGDALOX15SMN1; SMN2KDM4EPOLB | |
| SCHEMBL2169211 | 0.92 | ITK (0.38) | HPGDALOX15KDM4EPOLBMAPT | |
| SCHEMBL2168080 | 0.91 | POLB (0.36) | HPGDALOX15SMN1; SMN2KDM4EPOLB | |
| SCHEMBL2168910 | 0.91 | SMN1; SMN2 (0.42) | HPGDALOX15SMN1; SMN2KDM4EPOLB | |
| SCHEMBL2168083 | 0.88 | KDM5A (0.33) | HPGDALOX15SMN1; SMN2KDM4EPOLB | |
| SCHEMBL18887176 | 0.88 | HPGD (0.36) | HPGDALOX15SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2180684 | 0.87 | ADRA1A (0.37) | HPGDSMN1; SMN2ALDH1A1NPC1MAPK1 | |
| SCHEMBL2169080 | 0.87 | MCHR1 (0.37) | HPGDSMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL2169234 | 0.86 | MEN1 (0.34) | HPGDSMN1; SMN2KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |