Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21629522 | 0.90 | RAB9A (0.68) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21629548 | 0.90 | RAB9A (0.68) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21629546 | 0.90 | RAB9A (0.68) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21629511 | 0.90 | RAB9A (0.68) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30360876 | 0.90 | CYP3A4 (0.61) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21677134 | 0.89 | RAB9A (0.68) | RAB9AALDH1A1HPGDKDM4ECYP3A4 | |
| SCHEMBL30360892 | 0.89 | RAB9A (0.55) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21629603 | 0.89 | RAB9A (0.73) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21629619 | 0.89 | ALDH1A1 (0.72) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21629559 | 0.88 | RAB9A (0.65) | RAB9AALDH1A1HPGDKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3598972-A1 | 4-PHENYL-COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | Lead Discovery Center GmbH (DE) | 2020-01-29 | — | — | EP | disclosed |