Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18683297 | 1.00 | KCNN4 (0.39) | KCNN4KCNE1KCNQ1KIF11CTNNB1 | |
| SCHEMBL18683037 | 0.78 | USP28 (0.34) | — | |
| SCHEMBL20005896 | 0.78 | KCNN4 (0.39) | KCNN4KCNE1KCNQ1KIF11CTNNB1 | |
| SCHEMBL12077605 | 0.78 | KCNN4 (0.39) | KCNN4KCNE1KCNQ1KIF11CTNNB1 | |
| SCHEMBL21677293 | 0.75 | KCNN4 (0.47) | KCNN4KCNE1KCNQ1KIF11CTNNB1 | |
| SCHEMBL18683357 | 0.75 | KCNN4 (0.47) | KCNN4KCNE1KCNQ1KIF11CTNNB1 | |
| SCHEMBL28994163 | 0.75 | KCNN4 (0.38) | KCNN4KCNE1KCNQ1KIF11CTNNB1 | |
| SCHEMBL15480889 | 0.74 | KCNN4 (0.42) | KCNN4KCNE1KCNQ1KIF11CTNNB1 | |
| SCHEMBL15142455 | 0.73 | KCNN4 (0.35) | KCNN4KCNE1KCNQ1KIF11 | |
| SCHEMBL14165902 | 0.71 | KCNN4 (0.37) | KCNN4KCNE1KCNQ1KIF11CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353163-B1 | 2,3,4,5-TETRAHYDROPYRIDIN-6-AMINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-05 | — | — | EP | disclosed |