Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21664519 | 0.91 | GLS (0.31) | GLSMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21638837 | 0.89 | MEN1 (0.34) | GLSMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21677174 | 0.88 | GLS (0.33) | GLSMEN1KMT2AGPR119PDE4B | |
| SCHEMBL21638845 | 0.82 | EP300 (0.31) | MEN1KMT2AICAM1SELE | |
| SCHEMBL21638846 | 0.81 | GLS (0.31) | GLS | |
| SCHEMBL21677173 | 0.81 | NR1H2 (0.37) | GLSMEN1KMT2AGPR119EHMT2 | |
| SCHEMBL21677171 | 0.73 | NR1H2 (0.32) | GLSMAPTGPR119EHMT2 | |
| SCHEMBL21638843 | 0.73 | NR1H2 (0.35) | GLS | |
| SCHEMBL21677172 | 0.68 | GPR119 (0.38) | ALDH1A1MAPTGPR119 | |
| SCHEMBL21638838 | 0.67 | NR1H2 (0.34) | GLSALDH1A1GPR119EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025543-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2020-02-06 | — | — | WO | disclosed |