Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 15/20 | 0.89 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.89 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21632197 | 0.99 | NLRP3 (0.88) | NLRP3KCNH2SLC18A2TP53THRB | |
| SCHEMBL21632386 | 0.94 | NLRP3 (1.00) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632101 | 0.89 | NLRP3 (0.91) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632342 | 0.89 | NLRP3 (0.91) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632131 | 0.86 | NLRP3 (0.77) | NLRP3KCNH2SLC18A2TP53THRB | |
| SCHEMBL21632445 | 0.86 | NLRP3 (0.85) | NLRP3KCNH2SLC18A2TP53THRB | |
| SCHEMBL21677407 | 0.86 | NLRP3 (0.77) | NLRP3KCNH2SLC18A2TP53THRB | |
| SCHEMBL21632164 | 0.85 | NLRP3 (0.89) | NLRP3KCNH2SLC18A2TP53 | |
| Hydrochloric Acid SCHEMBL21632148 | 0.85 | NLRP3 (0.75) | NLRP3KCNH2SLC18A2TP53THRB | |
| SCHEMBL21632457 | 0.85 | NLRP3 (0.85) | NLRP3KCNH2SLC18A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210308140-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2021-10-07 | — | — | US | disclosed |
| WO-2020021447-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210308140-A1 | NLRP3 INFLAMMASOME INHIBITORS | NLRP3, NLRP1, NOD1 | NLRP3 1/4885KCNH2 1699/4885SLC18A2 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.