Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23743657 | 1.00 | L3MBTL1 (0.46) | L3MBTL1TDP1EPHX2ALDH1A1TEAD3 | |
| SCHEMBL1122003 | 0.94 | ALDH1A1 (0.45) | L3MBTL1TDP1EPHX2ALDH1A1TEAD3 | |
| SCHEMBL1122000 | 0.94 | ALDH1A1 (0.45) | L3MBTL1TDP1EPHX2ALDH1A1TEAD3 | |
| SCHEMBL1122130 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TEAD3CYP2C9TSHRHTT | |
| SCHEMBL721275 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TEAD3CYP2C9TSHRHTT | |
| SCHEMBL24703878 | 0.88 | L3MBTL1 (0.46) | L3MBTL1TDP1EPHX2ALDH1A1TEAD3 | |
| SCHEMBL23743658 | 0.88 | L3MBTL1 (0.46) | L3MBTL1TDP1EPHX2ALDH1A1TEAD3 | |
| SCHEMBL21677905 | 0.85 | NR1H4 (0.43) | L3MBTL1TDP1EPHX2ALDH1A1TEAD3 | |
| SCHEMBL1572986 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TEAD3NAAACYP2C9TSHR | |
| SCHEMBL1572988 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TEAD3NAAACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20220143038-A1 | LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF | PURETECH LYT, INC. (US) | 2022-05-12 | — | — | US | disclosed |
| US-20220125933-A1 | LIPID PRODRUGS OF JAK INHIBITORS AND USES THEREOF | SEAPORT THERAPEUTICS, INC. | 2022-04-28 | — | — | US | disclosed |
| US-20210300962-A1 | LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF | SEAPORT THERAPEUTICS, INC. | 2021-09-30 | — | — | US | disclosed |
| US-20200390777-A1 | LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF | SEAPORT THERAPEUTICS, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2020028787-A1 | LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF | PureTech Health LLC (US) | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | CYP21A2, CYP46A1, CYP17A1 | L3MBTL1 3485/4885TDP1 1452/4885EPHX2 130/4885 |
| US-20220125933-A1 | LIPID PRODRUGS OF JAK INHIBITORS AND USES THEREOF | JAK1, JAK2, JAK3 | L3MBTL1 1375/4885TDP1 1941/4885EPHX2 549/4885 |
| US-20200390777-A1 | LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF | MALT1, CYP2B6, LIPA | L3MBTL1 2320/4885TDP1 1969/4885EPHX2 487/4885 |
| US-20210300962-A1 | LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF | CYP21A2, CYP46A1, CYP17A1 | L3MBTL1 3700/4885TDP1 1706/4885EPHX2 163/4885 |
| US-20220143038-A1 | LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF | MALT1, CYP2B6, LIPA | L3MBTL1 2320/4885TDP1 1969/4885EPHX2 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.