Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644526 | 0.85 | PTGS1 (0.47) | TRPV1HSP90AA1HSP90AB1TRPA1ALOX15 | |
| SCHEMBL30779600 | 0.85 | PTGS1 (0.47) | TRPV1HSP90AA1HSP90AB1TRPA1ALOX15 | |
| SCHEMBL21644611 | 0.81 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1IGF1RALOX15 | |
| SCHEMBL30779644 | 0.81 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1IGF1RALOX15 | |
| SCHEMBL9156902 | 0.80 | BCL2 (0.58) | BCL2BCL2L1IGF1RALOX15ALOX5 | |
| SCHEMBL20920805 | 0.79 | IGF1R (0.53) | HSP90AA1GABRA1GABRB2IGF1RALOX15 | |
| SCHEMBL8409221 | 0.75 | GABRA1 (0.53) | TRPV1GABRA1GABRB2TRPA1 | |
| SCHEMBL31603746 | 0.75 | GABRA1 (0.53) | TRPV1GABRA1GABRB2TRPA1 | |
| SCHEMBL1343616 | 0.74 | HTR1A (0.44) | GABRA1GABRB2 | |
| SCHEMBL29511190 | 0.74 | HTR1A (0.44) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | TRPV1 3227/4885HSP90AA1 3/4885HSP90AB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.