⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937539 | 1.00 | — | — | |
| SCHEMBL196610 | 1.00 | — | — | |
| SCHEMBL16675422 | 0.93 | LMNA (0.53) | — | |
| SCHEMBL16675428 | 0.93 | LMNA (0.53) | — | |
| SCHEMBL195900 | 0.93 | LMNA (0.53) | — | |
| SCHEMBL8908272 | 0.91 | LMNA (0.68) | — | |
| SCHEMBL10868893 | 0.91 | LMNA (0.46) | — | |
| SCHEMBL31509461 | 0.91 | LMNA (0.68) | — | |
| SCHEMBL6476873 | 0.91 | LMNA (0.68) | — | |
| SCHEMBL4826374 | 0.91 | LMNA (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802132-B2 | Small molecules for inducing selective protein degradation and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-10-31 | — | — | US | disclosed |
| EP-2514812-B1 | Fragrance compositions and compounds | GIVAUDAN SA (CH) | 2018-10-03 | — | — | EP | disclosed |
| EP-2514812-A2 | Fragrance compositions and compounds | Givaudan Nederland Services B.V. (NL) | 2012-10-24 | — | — | EP | disclosed |
| US-8088725-B2 | Fragrance compositions and compounds | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2012-01-03 | — | — | US | disclosed |
| US-20100132249-A1 | Fragrance Compositions and Compounds | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-06-03 | — | — | US | disclosed |
| EP-2118249-A2 | FRAGRANCE COMPOSITIONS AND COMPOUNDS | Givaudan Nederland Services B.V. (NL) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008092678-A2 | FRAGRANCE COMPOSITIONS AND COMPOUNDS | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2008-08-07 | — | — | WO | disclosed |