Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21640081 | 0.98 | HPGD (0.52) | HPGDPKMUSP2SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL21640726 | 0.98 | HPGD (0.52) | HPGDPKMUSP2SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL21640489 | 0.97 | HPGD (0.53) | HPGDPKMUSP2SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL21639935 | 0.94 | HPGD (0.57) | HPGDPKMUSP2SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL29086095 | 0.88 | HPGD (0.47) | HPGDPKMUSP2SMN1; SMN2HTT | |
| SCHEMBL24322831 | 0.85 | HPGD (0.52) | HPGDPKMUSP2SMN1; SMN2HTT | |
| SCHEMBL19254900 | 0.85 | HPGD (0.65) | HPGDPKMUSP2SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL21641107 | 0.83 | NPC1 (0.41) | HPGDPKMUSP2SMN1; SMN2HTT | |
| SCHEMBL19254902 | 0.81 | HPGD (0.65) | HPGDPKMUSP2SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL21640103 | 0.78 | HPGD (0.49) | HPGDPKMUSP2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604305-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | Wakunaga Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |