Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21639935 | 0.88 | HPGD (0.57) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL21680230 | 0.85 | HPGD (0.53) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL24322667 | 0.85 | MAPT (0.47) | HPGDPKMTSHRSMN1; SMN2CYP2C9 | |
| Hydrochloric Acid SCHEMBL21640081 | 0.84 | HPGD (0.52) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21640726 | 0.84 | HPGD (0.52) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL19254900 | 0.83 | HPGD (0.65) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL19254902 | 0.83 | HPGD (0.65) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21640489 | 0.82 | HPGD (0.53) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29086095 | 0.80 | HPGD (0.47) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL10030564 | 0.76 | SLC6A1 (0.57) | TSHRSMN1; SMN2KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | HPGD 1284/4885PKM 4535/4885TSHR 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.