Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254902 | 0.96 | HPGD (0.65) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21639935 | 0.85 | HPGD (0.57) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL21680230 | 0.85 | HPGD (0.53) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL3436778 | 0.84 | PKM (0.71) | HPGDPKMTSHRSMN1; SMN2HTT | |
| SCHEMBL24494873 | 0.84 | PKM (0.60) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21640081 | 0.83 | HPGD (0.52) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21640726 | 0.83 | HPGD (0.52) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL24322831 | 0.83 | HPGD (0.52) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21640489 | 0.82 | HPGD (0.53) | HPGDPKMTSHRUSP2SMN1; SMN2 | |
| SCHEMBL11146778 | 0.81 | EPHX1 (0.63) | HPGDPKMTSHRSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247976-B2 | Synthetic ligands that modulate the activity of the RhlR quorum sensing receptor | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-02-15 | — | — | US | disclosed |
| US-20190144407-A1 | Synthetic Ligands that Modulate the Activity of the RhlR Quorum Sensing Receptor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-05-16 | — | — | US | disclosed |
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | PNISR, PGLS, QRFPR | HPGD 1821/4885PKM 2019/4885TSHR 303/4885 |
| US-20190144407-A1 | Synthetic Ligands that Modulate the Activity of the RhlR Quorum Sensing Receptor | AREG, QRFPR, GPR139 | HPGD 622/4885PKM 4418/4885TSHR 171/4885 |
| US-11247976-B2 | Synthetic ligands that modulate the activity of the RhlR quorum sensing receptor | AREG, QRFPR, GPR139 | HPGD 622/4885PKM 4418/4885TSHR 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.