Alcohol

Alcohol

SCHEMBL21680900

CCO.Nc1cccc(N)c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.67
CASP1 P29466 1/20 0.67
RECQL P46063 1/20 0.67
ALDH1A1 P00352 8/20 0.52
TDP1 Q9NUW8 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
TP53 P04637 1/20 0.52
NOS1 P29475 1/20 0.46
KDM4E B2RXH2 3/20 0.46
ENPP2 Q13822 1/20 0.46
MAOA P21397 3/20 0.44
MAOB P27338 2/20 0.44
TSHR P16473 2/20 0.44
MAPT P10636 1/20 0.44
CYP19A1 P11511 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28164094 0.97 CYP3A4 (0.63) CYP3A4CASP1RECQLALDH1A1TDP1
Alcohol SCHEMBL28175452 0.87 CYP3A4 (0.50) CYP3A4CASP1RECQLALDH1A1TDP1
Alcohol SCHEMBL10712196 0.85 ACHE (0.55) CYP3A4CASP1RECQLALDH1A1TDP1
Alcohol SCHEMBL11664175 0.85 ACHE (0.55) CYP3A4CASP1RECQLALDH1A1TDP1
Methyl Alcohol SCHEMBL27727278 0.85 CYP3A4 (0.80) CYP3A4CASP1RECQLALDH1A1TDP1
3-Aminophenol SCHEMBL27485936 0.84 ALDH1A1 (0.74) CYP3A4CASP1RECQLALDH1A1TDP1
Methyl Alcohol SCHEMBL27844489 0.82 CYP3A4 (0.75) CYP3A4CASP1RECQLALDH1A1TDP1
Ethane SCHEMBL21408539 0.82 CYP3A4 (0.86) CYP3A4CASP1RECQLALDH1A1TDP1
SCHEMBL11661863 0.82 CYP3A4 (1.00) CYP3A4CASP1RECQLALDH1A1TDP1
SCHEMBL1934399 0.82 CYP3A4 (1.00) CYP3A4CASP1RECQLALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290093-A Method for preparing self-repairing mortar by using active cement particle microcapsule 北京工业大学 2024-07-05 CN claimed
CN-112058094-B Loose nanofiltration membrane and preparation method thereof 贵州省材料产业技术研究院 2021-04-30 CN claimed
CN-111205703-B Crack visualized waterproof coating and preparation method thereof 西南大学 2021-04-09 CN claimed
CN-111205703-A Crack visualized waterproof coating and preparation method thereof 西南大学 2020-05-29 CN claimed
CN-118290093-A Method for preparing self-repairing mortar by using active cement particle microcapsule 北京工业大学 2024-07-05 CN disclosed
CN-110815965-B Fiber reinforced metal composite material and application thereof 嘉瑞制品有限公司 2023-07-21 CN disclosed
US-11618246-B2 Fiber reinforced metal composite and application thereof KA SHUI MANUFACTORY CO., LTD. (HK) 2023-04-04 US disclosed
US-11312108-B2 Fiber reinforced metal composite and application thereof KA SHUI MANUFACTORY CO., LTD. (HK) 2022-04-26 US disclosed
CN-112058094-B Loose nanofiltration membrane and preparation method thereof 贵州省材料产业技术研究院 2021-04-30 CN disclosed
CN-111205703-B Crack visualized waterproof coating and preparation method thereof 西南大学 2021-04-09 CN disclosed
US-20210060903-A1 FIBER REINFORCED METAL COMPOSITE AND APPLICATION THEREOF KA SHUI MANUFACTORY CO., LTD. (HK) 2021-03-04 US disclosed
CN-112058094-A Loose nanofiltration membrane and preparation method thereof 贵州省材料产业技术研究院 2020-12-11 CN disclosed
CN-102883803-B Delivery particles THE PROCTER & GAMBLE CO. (US) 2016-04-27 CN disclosed
CN-102892492-B Delivery of particles THE PROCTER & GAMBLE CO. (US) 2016-02-24 CN disclosed
CN-103622842-A Delivery particles PROCTER & GAMBLE 2014-03-12 CN disclosed
CN-103524420-A Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof PROCTER & GAMBLE 2014-01-22 CN disclosed
CN-102405036-B Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2013-09-18 CN disclosed
CN-102924962-A Method for preparing novel rhodamine laser dye UNIV EAST CHINA SCIENCE & TECH 2013-02-13 CN disclosed
CN-102924962-A Method for preparing novel rhodamine laser dye UNIV EAST CHINA SCIENCE & TECH 2013-02-13 CN disclosed
CN-102695492-A Thickened hair colourant and bleaching compositions PROCTER & GAMBLE 2012-09-26 CN disclosed