Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | ILK | Q13418 | 5/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29532912 | 0.79 | NPC1 (0.55) | NPC1RAB9AMAPTPOLBKDM4E | |
| SCHEMBL804637 | 0.79 | RAB9A (0.51) | NPC1RAB9AILKMAPTTDP1 | |
| SCHEMBL21682234 | 0.78 | LIMK1 (0.53) | NPC1RAB9AILKMAPTTDP1 | |
| SCHEMBL8854935 | 0.77 | RAB9A (0.50) | NPC1RAB9AILKMAPTTDP1 | |
| SCHEMBL6748668 | 0.77 | WDR5 (0.68) | NPC1WDR5MAPTTDP1POLB | |
| SCHEMBL5708178 | 0.77 | KDM4E (0.53) | NPC1RAB9AILKMAPTTDP1 | |
| SCHEMBL24156044 | 0.76 | CYP2A6 (0.46) | NPC1RAB9AILKMAPTTDP1 | |
| SCHEMBL5027039 | 0.76 | MAPT (0.63) | NPC1RAB9AILKMAPTTDP1 | |
| SCHEMBL2397424 | 0.75 | NPC1 (0.56) | NPC1RAB9AILKMAPTTDP1 | |
| SCHEMBL21681975 | 0.75 | MAPT (0.51) | NPC1RAB9AILKMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033782-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-1\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-13 | — | — | WO | claimed |
| WO-2020033782-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-1\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-13 | — | — | WO | disclosed |