Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 3/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17251803 | 0.90 | CASP3 (0.65) | SCDHTTHSD17B1HSD17B2LRRK2 | |
| SCHEMBL29532955 | 0.90 | CASP3 (0.65) | SCDHTTHSD17B1HSD17B2LRRK2 | |
| SCHEMBL21681925 | 0.86 | RAB9A (0.68) | SCDHTTLCKHSD17B1HSD17B2 | |
| SCHEMBL31398557 | 0.86 | HSD17B10 (0.67) | SCDHTTHSD17B1HSD17B2LRRK2 | |
| SCHEMBL21681919 | 0.84 | NPC1 (0.57) | SCDHTTHSD17B1HSD17B2CASP3 | |
| SCHEMBL14807588 | 0.83 | TOP1 (0.74) | SCDHTTCASP3SENP8SENP7 | |
| SCHEMBL6058291 | 0.83 | HTT (0.61) | SCDHTTLCKHSD17B1HSD17B2 | |
| SCHEMBL21682009 | 0.82 | CASP3 (0.65) | HSD17B1HSD17B2LRRK2CASP3SENP8 | |
| SCHEMBL21681916 | 0.82 | MAP3K5 (0.69) | SCDHTTHSD17B1HSD17B2LRRK2 | |
| SCHEMBL16553834 | 0.82 | SCD (1.00) | SCDHTTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037706-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HEPATITIS B VIRUS INFECTION | University of Washington (US) | 2022-08-10 | — | — | EP | claimed |
| WO-2021067480-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HEPATITIS B VIRUS INFECTION | UNIVERSITY OF WASHINGTON (US) | 2021-04-08 | — | — | WO | claimed |
| WO-2020033782-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-1\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-13 | — | — | WO | claimed |
| EP-4037706-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HEPATITIS B VIRUS INFECTION | University of Washington (US) | 2022-08-10 | — | — | EP | disclosed |
| WO-2021067480-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HEPATITIS B VIRUS INFECTION | UNIVERSITY OF WASHINGTON (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2020033782-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-1\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-13 | — | — | WO | disclosed |