SCHEMBL2168541

SCHEMBL2168541

CC=CC1C(C(=O)OCC)C1(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
TSHR P16473 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HTT P42858 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 5/20 0.36
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ADRA2A P08913 1/20 0.33
CNR1 P21554 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29246835 1.00 LMNA (0.67) LMNATSHRTDP1MEN1KMT2A
SCHEMBL2170337 1.00 LMNA (0.67) LMNATSHRTDP1MEN1KMT2A
SCHEMBL2168536 1.00 LMNA (0.67) LMNATSHRTDP1MEN1KMT2A
SCHEMBL2166576 0.86 LMNA (0.50) LMNATSHRTDP1MEN1KMT2A
SCHEMBL2166578 0.86 LMNA (0.50) LMNATSHRTDP1MEN1KMT2A
SCHEMBL2169791 0.86 LMNA (0.50) LMNATSHRTDP1MEN1KMT2A
SCHEMBL3696141 0.84 LMNA (0.49) LMNATSHRHTTKDM4EALDH1A1
SCHEMBL3696144 0.84 LMNA (0.49) LMNATSHRHTTKDM4EALDH1A1
SCHEMBL9797004 0.84 LMNA (0.65) LMNATSHRTDP1MEN1KMT2A
SCHEMBL3683589 0.84 LMNA (0.65) LMNATSHRTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030032839-A1 Process for racemizing optically active vinyl-substituted cyclopropanecarboxylic acid compound PANASONIC CORPORATION (JP) 2003-02-13 US claimed
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP disclosed
EP-1547995-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
EP-1681282-B1 METHOD FOR PRODUCING 3,3-DIMETHYL-2-(1-PROPENYL) CYCLOPROPANE CARBOXYLATE SUMITOMO CHEMICAL CO (JP) 2013-01-23 EP disclosed
EP-1970368-B1 METHOD FOR PRODUCING OLEFIN COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-08-29 EP disclosed
US-7985872-B2 Method for producing olefin compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-26 US disclosed
CN-1874990-B Method for producing 3,3-dimethyl-2-(1-propenyl)cyclopropane carboxylic acid ester SUMITOMO CHEMICAL CO 2011-06-29 CN disclosed
CN-1934063-B Method for producing (2-formyl-1-alkenyl)cyclopropane compound SUMITOMO CHEMICAL CO 2010-12-15 CN disclosed
CN-1660764-B Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO 2010-12-08 CN disclosed
US-7741511-B2 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20050090688-A1 Metallized mesoporous silicate and method of oxidation with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-28 US disclosed
EP-1473275-A1 METALLIZED MESOPOROUS SILICATE AND METHOD OF OXIDATION WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-11-03 EP disclosed
US-20040152592-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMTED 2004-08-05 US disclosed
US-6750370-B2 CHEMICAL INTERMEDIATE FOR SYNTHETIC PYRETHROIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-15 US disclosed
US-6703528-B2 CATALYTIC OXIDATION OF OLEFIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-09 US disclosed
EP-1377584-A1 NOVEL CYCLOHEXENYL PHENYL DIAZEPINES AS VASOPRESSIN AND OXYTOCIN RECEPTOR MODULATORS Wyeth (US) 2004-01-07 EP disclosed
US-20030032839-A1 Process for racemizing optically active vinyl-substituted cyclopropanecarboxylic acid compound PANASONIC CORPORATION (JP) 2003-02-13 US disclosed
WO-2002083681-A1 NOVEL CYCLOHEXENYL PHENYL DIAZEPINES VASOPRESSIN AND OXYTOCIN RECEPTOR MODULATORS WYETH (US) 2002-10-24 WO disclosed
EP-1188735-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-20 EP disclosed
US-20020025906-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032839-A1 Process for racemizing optically active vinyl-substituted cyclopropanecarboxylic acid compound NOS1, CYP1B1, CBR1 LMNA 2790/4885TSHR 3624/4885TDP1 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.