SCHEMBL21687565

SCHEMBL21687565

N#Cc1ccc2c(c1)c1ccccc1n2-c1ccc(C#N)c(-c2c(C#N)cccc2[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 7/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
RARG P13631 1/20 0.31
HRH1 P35367 1/20 0.31
HTR6 P50406 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21687931 0.93 ALDH1A1 (0.36) ALDH1A1LMNAHPGDMAPK1SMN1; SMN2
SCHEMBL21687933 0.92 ALDH1A1 (0.32) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21688019 0.89 ALDH1A1 (0.34) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21688016 0.88 KDM4E (0.34) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21687689 0.88 KDM4E (0.34) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21688064 0.87 ALDH1A1 (0.32) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21687509 0.87 ALDH1A1 (0.34) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21687530 0.87 ALDH1A1 (0.34) TDP2ALDH1A1LMNAHPGDMAPK1
SCHEMBL21688020 0.86 HRH1 (0.35) TDP2SMN1; SMN2HRH1HTR6
SCHEMBL21687562 0.86 HRH1 (0.32) HRH1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-14 US disclosed
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND CRY1, CCNL2, CCNE2 TDP2 4123/4885ALDH1A1 616/4885LMNA 1582/4885
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound CRY1, CCNL2, CCNE2 TDP2 4123/4885ALDH1A1 616/4885LMNA 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.