SCHEMBL21687569

SCHEMBL21687569

N#Cc1ccc(-c2c(C#N)cccc2[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c(-n2c3ccccc3c3cc(C#N)ccc32)c1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.33
HTR6 P50406 1/20 0.33
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21687789 0.97 HRH1 (0.31) HRH1HTR6PTGER4
SCHEMBL21688020 0.94 HRH1 (0.35) HRH1HTR6PTGER4
SCHEMBL21687562 0.92 HRH1 (0.32) HRH1HTR6PTGER4
SCHEMBL21688009 0.91 HRH1 (0.35) HRH1HTR6
SCHEMBL21688249 0.90 SMN1; SMN2 (0.36) HRH1HTR6
SCHEMBL21688071 0.90 HRH1 (0.34) HRH1HTR6PTGER4
SCHEMBL21688186 0.89 MAPT (0.32) PTGER4
SCHEMBL21687933 0.88 ALDH1A1 (0.32) HRH1HTR6
SCHEMBL21688114 0.88 HRH1 (0.33) HRH1HTR6PTGER4
SCHEMBL21687875 0.88 HRH1 (0.32) HRH1HTR6PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-14 US disclosed
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200044168-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND CRY1, CCNL2, CCNE2 HRH1 1158/4885HTR6 3591/4885PTGER4 553/4885
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound CRY1, CCNL2, CCNE2 HRH1 1158/4885HTR6 3591/4885PTGER4 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.