SCHEMBL21689084

SCHEMBL21689084

Cc1ccncc1CC#N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.40
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2E1 P05181 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP2C19 P33261 1/20 0.40
TNF P01375 1/20 0.37
SIRT3 Q9NTG7 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CCNC P24863 1/20 0.36
CDK8 P49336 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRA5 P31644 1/20 0.35
AOC1 P19801 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31456366 0.84 AOC1 (0.39) CYP17A1CYP11B1CYP11B2CYP1A2CYP2E1
SCHEMBL37676938 0.81 TNF (0.40) CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9
SCHEMBL3670639 0.81 TNF (0.40) CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9
SCHEMBL23674611 0.78 CCNC (0.44) CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6
SCHEMBL17807363 0.76 GAA (0.38) CYP2A6TNFCCNCCDK8SLC6A2
SCHEMBL27165746 0.76 TNF (0.37) TNFCCNCCDK8AOC1AOC3
SCHEMBL3074174 0.76 HTT (0.42) CYP11B1CYP11B2TNFCCNCCDK8
SCHEMBL11940513 0.74 TNF (0.36) CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9
SCHEMBL11940514 0.74 TNF (0.36) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL30335585 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604326-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM Corporation (JP) 2020-02-05 EP disclosed