SCHEMBL21689255

SCHEMBL21689255

NC(=O)c1coc(-c2ccc(N)cc2)n1

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.73
HDAC1 Q13547 8/20 0.50
HDAC8 Q9BY41 8/20 0.50
HDAC6 Q9UBN7 8/20 0.50
PDE4B Q07343 8/20 0.43
ELANE P08246 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
IKBKB O14920 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27808017 0.86 ALDH1A1 (0.73) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL168220 0.85 ALDH1A1 (0.71) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL28033118 0.85 ALDH1A1 (0.71) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL893099 0.84 ALDH1A1 (1.00) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL27721487 0.83 ALDH1A1 (0.73) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL2823348 0.81 HDAC1 (0.55) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL13819985 0.81 HDAC1 (0.70) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL1385110 0.77 ALDH1A1 (0.60) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL20338978 0.77 ALDH1A1 (0.60) ALDH1A1HDAC1HDAC8HDAC6PDE4B
SCHEMBL24339961 0.77 ELANE (0.53) ALDH1A1HDAC1HDAC8HDAC6ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604326-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM Corporation (JP) 2020-02-05 EP disclosed