Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16893950 | 0.81 | GAA (0.54) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL8933555 | 0.76 | GAA (0.48) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL103606 | 0.73 | GAA (0.45) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL30166019 | 0.73 | LMNA (0.45) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL28117337 | 0.73 | ATAD2 (0.41) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL18640389 | 0.72 | GAA (0.44) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL1918404 | 0.71 | ATAD2 (0.52) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL8537479 | 0.71 | MAPT (0.52) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL11417188 | 0.71 | DPYD (0.46) | DPYDGAAATAD2MAPTALDH1A1 | |
| SCHEMBL7668285 | 0.71 | DPYD (0.46) | DPYDGAAATAD2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106255697-B | Phosphorus protecting group and preparation method and application thereof | 安捷伦科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-106255697-A | Phosphorus protecting group and preparation method and application thereof | 安捷伦科技有限公司 | 2016-12-21 | — | — | CN | disclosed |
| EP-2348117-A1 | Arabidopsis genes encoding proteins involved in sugar and lipid metabolism and methods of use | BASF Plant Science GmbH (DE) | 2011-07-27 | — | — | EP | disclosed |