Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168860 | 0.86 | LMNA (0.40) | MAPTLMNATP53POLBOPRM1 | |
| SCHEMBL18887202 | 0.86 | LMNA (0.41) | MAPTLMNATP53POLBOPRM1 | |
| SCHEMBL2170222 | 0.85 | MAPT (0.39) | MAPTLMNATP53POLBHPGD | |
| SCHEMBL2184240 | 0.84 | HRH3 (0.44) | MAPTLMNATP53POLBHPGD | |
| SCHEMBL2168038 | 0.84 | HPGD (0.43) | MAPTLMNATP53POLBHPGD | |
| SCHEMBL2169831 | 0.81 | HPGD (0.40) | MAPTLMNATP53POLBHPGD | |
| SCHEMBL2171193 | 0.81 | HPGD (0.39) | MAPTLMNATP53POLBHPGD | |
| SCHEMBL2168080 | 0.81 | POLB (0.36) | MAPTLMNATP53POLBHPGD | |
| SCHEMBL2171166 | 0.81 | MEN1 (0.44) | MAPTLMNATP53POLBHPGD | |
| SCHEMBL2169211 | 0.80 | ITK (0.38) | MAPTLMNATP53POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |