Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167838 | 0.89 | MAPT (0.35) | MAPTLMNATP53POLBHDAC8 | |
| SCHEMBL18887192 | 0.87 | MAPT (0.37) | MAPTLMNATP53POLBSMN1; SMN2 | |
| SCHEMBL2184240 | 0.86 | HRH3 (0.44) | MAPTLMNATP53POLBSMN1; SMN2 | |
| SCHEMBL2169151 | 0.85 | MAPT (0.42) | MAPTLMNATP53POLBHDAC8 | |
| SCHEMBL2171166 | 0.83 | MEN1 (0.44) | MAPTLMNATP53POLBSMN1; SMN2 | |
| SCHEMBL2168910 | 0.82 | SMN1; SMN2 (0.42) | MAPTLMNATP53POLBSMN1; SMN2 | |
| SCHEMBL2170216 | 0.82 | NPC1 (0.43) | MAPTLMNATP53POLBSMN1; SMN2 | |
| SCHEMBL2169312 | 0.82 | ALDH1A1 (0.45) | LMNATP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2167362 | 0.81 | HRH3 (0.41) | MAPTLMNATP53POLBSMN1; SMN2 | |
| SCHEMBL2168038 | 0.80 | HPGD (0.43) | MAPTLMNATP53POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |